Standard- Versus Reduced-Dose Apixaban and Vitamin K Antagonists in Patients with Atrial Fibrillation and Advanced Chronic Kidney Disease: A Systematic Review and Network Meta-Analysis

J Clin Med · 2026 · PMC13301731

Europe PMC

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showed a trendno p-value reported

Only standard-dose apixaban showed a trend toward lower mortality compared with VKAs (HR 0.87, 95% CI 0.76–1.00) ( Supplementary Figure S4 ).

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