Changes in HDAC Expression and Activity by Oolongtheanin Digallate and Theasinensins and the Onset of Apoptosis.

Molecules · 2026 · PMC13304866 · PMID 42357499

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highly significantno p-value reported

In addition, OTDG at the highest tested concentration caused a significant decrease in TP53 transcription and a highly significant decrease in BCL2 transcription.

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did not reach statistical significanceno p-value reported

Incubation with TSA caused a highly significant decrease in caspase-9 activity to −0.020 nmol/(mg·min), whereas its atropisomer TSD increased caspase-9 activity, although this effect did not reach statistical significance.

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