Homologous recombination deficiency correlates with tumor-infiltrating lymphocytes and predicts patient outcomes in hormone receptor-positive/HER2-negative breast cancer.

Patients in the anthracycline group also displayed a trend toward more aggressive disease features, although these differences did not reach statistical significance.

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The results showed that the four subgroups defined by HRD and TILs status had highly significant differences in IDFS, DRFS, and OS, but the subgroup analysis revealed that the level of TILs did not allow for stratification of the prognosis based on different HRD statuses ( Table S8 ).

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