Model-Based Virtual Clinical Trial Reveals Renal Impairment and Body Size as Key Determinants of Pharmacokinetic Variability and Drug-Drug Interaction Risk in Propranolol Therapy.

Pharmaceutics · 2026 · PMC13306096 · PMID 42357253

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did not reach statistical significanceno p-value reported

Although a slight reduction in PROP clearance was observed, it did not reach statistical significance within the study design.

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