Ultra-Early OCT Changes After Intravitreal Injection: Evidence Consistent with Transient Mechanical Compression.

Vision (Basel) · 2026 · PMC13307848 · PMID 42347571

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.1800

boldest claim

The sentences

highly significantp < 0.001actually significant

Intraocular Pressure Dynamics Repeated-measures ANOVA revealed a highly significant main effect of time on IOP [F(1.8, 70.2) = 312.5, p < 0.001, partial η 2 = 0.89].

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did not reach statistical significancep = 0.180not close (p > 0.1)

Temporal Evolution of Macular Thickness At 24 h post-injection, substantial rebound was observed: mean CST reduction was only −3.0 ± 7.5% (95% CI: −5.4% to −0.6%), which did not reach statistical significance after Bonferroni correction ( p = 0.180).

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