Barely Significant
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Relationship between single point insulin sensitivity estimator index and nonalcoholic fatty liver disease in Chinese middle-aged and older adults: a cross-sectional study.

Front Nutr · 2026 · PMC13310994 · PMID 42375775

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However, while the direction of this inverse association was generally consistent with the primary analysis ( Table 3 ), it did not reach statistical significance (i.e., the 95% CI crossed 1.0) in certain strata.

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a decreasing trendno p-value reported
The proportion of participants aged 50–59 years overall exhibited a decreasing trend with ascending SPISE index quartiles, declining from 48.99% in Q1 to 37.94% in Q4.

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