Barely Significant
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Developing and validating a lactate-to-albumin ratio-enhanced score for mortality prediction in ICU patients with acute pulmonary embolism: a multi-cohort study.

Front Med (Lausanne) · 2026 · PMC13311097 · PMID 42375206

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closest p · 0.0× alpha
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The sentences

highly significantP < 0.001actually significant
In the first validation cohort, RCS analysis identified a highly significant association (overall P < 0.001) with a significant nonlinear trend ( P for nonlinearity = 0.011), whereas a linear association was observed again in the second validation cohort (overall P < 0.001, P for nonlinearity = 0.068).

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In the derivation cohort, Q1 and Q2 showed significantly lower mortality risk in unadjusted and partially adjusted models, whereas the fully adjusted model (Model 3) did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.