Dihydropyridine Calcium Channel Blocker Therapy and Risk of CKD Progression in Type 2 Diabetes Treated With Renin Angiotensin System Inhibitors and SGLT2 Inhibitors: A Real-World Retrospective Cohort Study.

Kidney Med · 2026 · PMC13311150 · PMID 42375684

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0700

boldest claim

The sentences

showed a trendP = 0.06so close (0.05 < p ≤ 0.1)

In IPTW-weighted analyses, the associations showed a trend toward significance (HR, 1.37; 95% CI, 0.98-1.92; P = 0.06) and became significant in competing risk models (HR, 1.43; 95% CI, 1.04-1.97; P = 0.03; E-value, 1.24).

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a trend toward significanceP = 0.07so close (0.05 < p ≤ 0.1)

In the IPTW-weighted analyses, this association attenuated and showed only a trend toward significance in competing risk models (HR, 1.42; 95% CI, 0.97-2.08; P = 0.07).

also in 3,729 other papers

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