Barely Significant
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Prospective randomised controlled trial to compare tissue reactions and scarring with polypropylene versus polyglactin 910 sutures in periocular skin.

Br J Ophthalmol · 2026 · PMC13311939 · PMID 41386795

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There was an approximately 50% larger mean diameter of inflammation around the Vicryl than Prolene sutures, and the median histological grade sum (a summative measure of histological inflammation) was 25% higher around the Vicryl than the Prolene, but this did not reach statistical significance; the postulated effect size was 1.0 and the observed effect size was 0.51 (95% CI −0.22 to 1.21).

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