Pairwise comparisons across time points indicated that the 6 dpi immune transcriptional program was time-restricted, with most genes returning to mock-like levels by 15 dpi, whereas Hcrt expression showed a trend toward recovery throughout the post-acute phase (Supplementary Fig. 6).
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SARS-CoV-2 infection is associated with hypothalamic orexin suppression and persistent cortical NeuN attenuation.
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