slightly significantp < 0.0267
As shown in Figure 9 , the secretion of IL-1β cytokine from normal REF with first and second concentrations (groups) of microbial-extracted pigment was slightly significant compared with the control group: 2,067.5 μg/ml ( p < 0.0267) and 1,033.75 μg/ml ( p < 0.0348).