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Downregulation of ANKRD22 promotes ovarian cancer cell proliferation by enhancing the immunosuppressive capacity of M-MDSCs.

Cancer Immunol Immunother · 2026 · PMC13315053 · PMID 42373967

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Ki67 staining revealed that direct contact consistently induced stronger ID8 cell proliferation than indirect contact did across all ratios, while both conditions showed a clear dose-dependent relationship (strongest effect at 1:10, although some pairwise comparisons did not reach statistical significance).

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