Targeting central immune signaling enhances the effects of methylphenidate in alleviating apathy-like behavior in 5xFAD mice.

Sci Rep · 2026 · PMC13315626 · PMID 42034805

Europe PMC DOI

hedged sentence

0.0979

closest p · 2.0× alpha

0.0979

boldest claim

The sentences

showed a trendp = 0.0979so close (0.05 < p ≤ 0.1)

However, 5xFAD mice treated with a combination of SB290157 and methylphenidate showed a trend towards improved DI when compared to 5xFAD with vehicle ( p = 0.0979, Fig. 5 e).

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