Ganoderma lucidum spore powder enhances IFN-α-mediated antiviral capacity of COVID-19 vaccine boosters revealed by single-cell multi-omics sequencing.

In contrast, the proportion of αLPs showed a decreasing trend after the vaccination, with an even more pronounced decrease observed after the GLSP intervention.

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While GD2 and GH at 10 μg/mL showed a strong trend of IFI44L induction, the most robust and significant effects were centered on ISG15 , a core ubiquitin-like effector in the interferon response [ 112 ].

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