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FGF21-FGFR1 signaling protects against cardiac hypertrophy by regulating PINK1-mediated mitophagy pathway.

J Adv Res · 2026 · PMC13316545 · PMID 41173187

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The TEM results revealed that the number of elongated mitochondria increased in the Fgf21 -/- mice post-TAC, although these changes did not reach statistical significance ( Fig. 2A ).

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