27 Although the overall group × time interaction for lactate did not reach statistical significance, lactate levels at the end of surgery were significantly lower in the dexmedetomidine group compared with the control group, even within the normal range, suggesting a possible improvement in global tissue perfusion and oxygen supply-demand balance, consistent with its hemodynamic stabilizing action.
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Effect of Titrated Dexmedetomidine versus Esmolol on Postoperative Myocardial Injury in High-Risk Patients Undergoing Laparoscopic Colorectal Cancer Surgery: A Randomized Controlled Trial.
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