Comparison of Urobiome and Urine pH in Women with or without Overactive Bladder Symptoms.

4 However, although our findings showed a trend toward lower bacterial diversity in the OAB group, they did not support this hypothesis, consistent with other studies that found no significant changes in diversity. 12 , 13 Previous studies comparing urine and vaginal bacteria in individuals with and without UUI found no differences in diversity but noted differences in Lactobacillus species between the two groups. 13 , 21 This finding suggests that the key distinction might not be in the overall diversity of the urinary microbiome but rather in the specific types of bacteria present.

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An interesting trend was noted, however, with Kocuria spp. associated with low urine pH and Corynebacteriaceae associated with high urine pH.

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