Chemokine-Receptor Modulation Shapes Neuroinflammatory and Biomechanical Responses in Organotypic Hippocampal Cultures After Oxygen-Glucose Deprivation.

ACS Chem Neurosci · 2026 · PMC13318064 · PMID 42139630

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did not reach statistical significancep = 0.1so close (0.05 < p ≤ 0.1)

Consequently, modulation of its receptor CX3CR1 using the selective antagonist AZD8797 showed a trend toward decreased LDH release in OGD-subjected OHCs, although it did not reach statistical significance ( t -test, p = 0.1) ( Figure A).

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