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Impact of Virtual Reality-Based Therapies on Cognition and Depression in Patients With Parkinson Disease: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

JMIR Serious Games · 2026 · PMC13318082 · PMID 42378559

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Thus, the positive trend observed in some domains might have been substantial enough, in aggregate, to drive the significant improvement in the more sensitive global cognitive score, even if each individual domain’s effect did not reach statistical significance in isolation.

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