CXCL5 is associated with neutrophil-driven intestinal inflammation and IL-17-associated epithelial signaling in inflammatory bowel disease.

Sci Rep · 2026 · PMC13319109 · PMID 42056229

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did not reach statistical significanceno p-value reported

Inflammatory cytokine analysis revealed that TNF-α expression was significantly lower in CXCL5 DKO colons, whereas IL-17A expression did not reach statistical significance.

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a decreasing trendno p-value reported

Notably, IL-17A expression was significantly reduced in CXCL5 KO mice (* p-value < 0.05), while TNF-α showed a decreasing trend without reaching statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.