Correlations between ONS volumes and ICP in the normal pressure subgroup narrowly missed statistical significance.
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Structural MRI Biomarkers of Intracranial Pressure in IIH: Linking Optic Nerve Sheath, Pituitary Morphology, and Hormonal Changes.
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The sentences
For ONS volumes, correlation coefficients in the normal ICP subgroup were relatively high and p -values narrowly missed significance.
This near-significant pattern is consistent with the expected biomechanics of raised intracranial pressure: the ONS serves as a distensible CSF-filled compartment and therefore expands early in the course of ICP elevation.