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A macrophage MHC-I axis links intratumoral heterogeneity to terminal CD8<sup>+</sup> T cell exhaustion in lung adenocarcinoma.

NPJ Precis Oncol · 2026 · PMC13319471 · PMID 42031958

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In our cohort, STK11-mutant cases were slightly more frequent in the ITH-High group than in the ITH-Low group, while this difference did not reach statistical significance (Fig. 1D ).

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