Evaluating the effects of glutaraldehyde concentration and incubation time on the structural integrity of the human pericardium.

Detailed subject-specific regression analyses based on linear mixed-effects models are provided in the Supplementary Material to support these findings, as well as additional mechanical parameters that did not reach statistical significance for completeness. 3.4 Correlation analysis To further assess relationships between structural and mechanical parameters, a within-person repeated-measures correlation (rmcorr) analysis was performed ( Figure 7 ; Carpentier et al., 1969 ).

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The 5-min incubation group showed a decreasing trend in transition strain with increasing GA concentration (slope = −1.22, R 2 = 0.33), which may suggest earlier collagen fiber alignment under mechanical load ( Figure 6C ).

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