Barely Significant
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Loss of O-antigen due to <i>wbbL</i> mutations is common and associated with increased mortality in <i>Escherichia coli</i> bloodstream infections.

Sci Adv · 2026 · PMC13322237 · PMID 42384788

Europe PMCDOI
2
hedged sentences
0.0537
closest p · 1.1× alpha
0.1500
boldest claim

The sentences

did not reach statistical significanceP = 0.0537so close (0.05 < p ≤ 0.1)
Urine isolates demonstrated a numerically higher proportion of mutations than bloodstream isolates (18.3% versus 8.3%), although this difference did not reach statistical significance (Fisher’s exact P = 0.0537).

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a trend toward significanceP ≤ 0.15not close (p > 0.1)
Variables demonstrating a trend toward significance ( P ≤ 0.15) in the univariable analysis were included in the multivariable logistic regression model.

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