Temporal dynamics and determinants of early recurrence after curative resection for stage I-III rectal cancer: integrated analyses of hazard function, survival, and competing risks.

Stratified cumulative incidence curves further showed that differences in local recurrence did not reach statistical significance across groups defined by LNR, T stage, CEA, or tumor differentiation, whereas differences in distant metastasis were statistically significant across all of these stratifications ( Figure 5 ).

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