Effect of diabetes on the efficacy and safety of <i>Panax notoginseng</i> saponins in ischemic stroke: a prespecified analysis of the PANDA trial.

Meanwhile, both patients without previous diabetes and those with fasting blood glucose levels below 7.0 mmol/L at baseline presented a trend toward benefiting from treatment with Xuesaitong soft capsules, although the subgroup interaction tests did not reach statistical significance. 4.2 Mechanistic hypothesis We hypothesized that multiple mechanisms involved in the pathobiology of ischemic stroke in patients with diabetes or treated hyperglycemia during hospitalization may modulate the efficacy of cerebroprotective agents like PNS.

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