A Randomized Controlled Trial Comparing Two Infusion Doses of Dexmedetomidine on Hemodynamic Response and Extubation Quality in Neurosurgical Patients.

Cureus · 2026 · PMC13324039 · PMID 42395243

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.1070

boldest claim

The sentences

highly significantp < 0.001actually significant

From 10 minutes until post-extubation and up to 1 hour postoperatively, MAP differences among the groups were highly significant (p < 0.001), with Groups D1 and D2 consistently showing lower values than Group C.

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did not reach statistical significancep = 0.107not close (p > 0.1)

While the mean time to extubation was longer in the D2 group (15.57 ± 1.94 min) compared to the D1 (12.9 ± 1.82 min) and C (11.77 ± 1.69 min) groups, this difference did not reach statistical significance (p = 0.107).

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