nominally significantP = 0.01
When examining POAG odds across UA PRS tertiles, no clear associations were observed in either cohort, except for one nominally significant finding in LifeLines after excluding possible cases, where the middle tertile showed higher odds of POAG (OR = 2.21, 95% CI = 1.18–4.13, P = 0.01; Supplementary Table S5 ).