Extralevator Abdominoperineal Excision Improves Overall Survival Compared to Standard Abdominoperineal Excision: A Systematic Review and Meta-Analysis.

Ann Gastroenterol Surg · 2026 · PMC13327026 · PMID 42395128

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did not reach statistical significanceno p-value reported

Local Recurrence‐Free Survival Data from four studies suggested a 33% lower risk of LR in the ELAPE group over the entire follow‐up period, but the results did not reach statistical significance (HR: 0.67, CI: 0.45–1.00 from IPD—see Figure 6 ; HR: 0.67, CI: 0.2–2.25 from aggregated data—see Figure S15 ).

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