Association of cumulative exposure and dynamic trajectories of the C-reactive protein-triglyceride-glucose and its modified indices with cardiovascular disease in individuals with cardiovascular-kidney-metabolic syndrome stages 0-3: a longitudinal analysis based on CHARLS.

Cardiovasc Diabetol · 2026 · PMC13330237 · PMID 42116161

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failed to reach statistical significanceno p-value reported

For discrimination, the AUC increments for all modified indices, including CTI-CVAI (AUC difference: 0.017, P = 0.076), failed to reach statistical significance.

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highly significantno p-value reported

The competing risk analyses objectively confirmed that all indices maintained robust and highly significant associations with incident CVD, independent of the competing risk of non-CVD death.

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