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The effect of the integrated stress response reduction intervention on cellular aging in middle-aged nurses: a pilot study.

BMC Nurs · 2026 · PMC13330248 · PMID 42288813

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While the group ⋅ time interaction analysis did not reach statistical significance for certain markers, especially LTL, the significant between-group differences observed post-intervention should be interpreted cautiously as exploratory evidence of relative LTL preservation, suggesting an initial protective effect rather than a definitive mitigation of cellular aging.

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