Glucokinase activity suppresses hepatic cholesterol synthesis and triglyceride accumulation: A new model for the effects of the GKRP P466L common human variant.

Mol Metab · 2026 · PMC13330626 · PMID 42309256

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showed a trendno p-value reported

Hepatic TAG levels increased (∼3-fold) in L-GCK-KO mice compared with controls under fasting conditions and showed a trend toward higher levels in the refed state ( Fig. 3 G).

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