Common and rare variant analyses implicate <i>JARID2</i> in cerebral tau deposition.

In addition, we identified 61 genes that were nominally significant association ( P < 0.05) with both tau and amyloid deposition including APOE , TOMM40 , and COL5A2 ( P < 0.005) with both tau and amyloid pathologies (Supplementary Fig. 4 and Supplementary Table 13 ).

also in 7,732 other papers

Hippocampal sclerosis, likely mediated by tau, occurs specifically among APOE non-ε4 carriers, though its association with tau PRS showed only a trend towards significance.

also in 2,760 other papers