Barely Significant
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Mutation-specific neuropathologic signatures in MAPT-associated frontotemporal lobar degeneration.

Acta Neuropathol · 2026 · PMC13331856 · PMID 42399565

Europe PMCDOI
1
hedged sentence
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closest p · 1.0× alpha
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boldest claim

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nominally significantp < 0.05actually significant
The most nominally significant transcripts in P301L included stress-response and glial markers (HSPB1, GFAP, DDIT3; p < 0.05), and in L284L included neuronal activity and disease-associated markers (FOS, ATXN2; p < 0.05) (Fig. 7 b, c, e, f).

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