nominally significantp < 0.05
We observed 1054 (7.7%) nominally significant associations ( p < 0.05; Supplementary Data 2 ), and 21 associations (0.2%) were statistically significant at a 5% false discovery rate (FDR), corresponding to p < 6.76 × 10 −5 (Figs. 2 and 3 and Table 1 ).