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Increased Arrhythmic Risk in Obesity Is Transduced by Adipose Tissue-Derived Extracellular Vesicles.

JACC Basic Transl Sci · 2026 · PMC13332671 · PMID 42334118

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However, although we noted a trend towards increased heart-weight and markers of pathologic hypertrophy, the weight of the ventricles normalized by tibial length ( Supplemental Figures 7B and 8B ), markers of molecular hypertrophy ( Supplemental Figure 8C ), the degree of histologic cardiac interstitial and perivascular fibrosis ( Supplemental Figures 7C to 7F ), or markers of molecular fibrosis ( Supplemental Figure 8D ) did not reach statistical significance between the 2 groups.

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