Renal cell carcinoma risk among individuals heterozygous for fumarate hydratase variants: further insights into genotype-phenotype correlations.

Hered Cancer Clin Pract · 2026 · PMC13335062 · PMID 42120995

Europe PMC DOI

hedged sentence

0.2800

closest p · 5.6× alpha

0.2800

boldest claim

The sentences

did not reach statistical significancep = 0.28not close (p > 0.1)

5 in FH-TPS-HLRCC) did not reach statistical significance between groups ( p = 0.28 and 0.28, respectively), while the difference in FH-deficient RCC did reach statistical significance (0 in FH-ARC vs. 5 in FH-TPS-HLRCC; p = 0.01; two-tailed Fisher’s exact test).

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