Microglia-Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis-Associated Encephalopathy.

Adv Sci (Weinh) · 2026 · PMC13335498 · PMID 42037180

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did not reach statistical significanceno p-value reported

Although a slight upward trend was observed within 12 h, this increase did not reach statistical significance, indicating that the tight junctions of the intact BBB effectively restricted passive diffusion of the nanoparticles.

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