The causal impact of gut microbiota on allergic rhinitis mediated by cerebrospinal fluid metabolites: A study based on Mendelian randomization and mediation analysis.

Medicine (Baltimore) · 2026 · PMC13336981 · PMID 42410803

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hedged sentence

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closest p · 1.0× alpha

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boldest claim

The sentences

nominally significantP < .05actually significant

After sensitivity analysis and FDR correction, the following results were obtained: Two-sample MR analyses using various brain-related omics datasets and ADs revealed that in the CSF metabolites-ADs analysis, several diseases exhibited nominally significant causal relationships ( P < .05) in the initial analysis.

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