Time Series Analysis for Physiological and Endocrinological Data: A Practical Guide.

Integr Comp Biol · 2026 · PMC13339088 · PMID 42314067

Europe PMC DOI

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a negative trendno p-value reported

Estrogen and progesterone in adult females may decline throughout life as individuals go through menopause or senescence, a negative trend.

also in 2,741 other papers

a positive trendno p-value reported

For example, testosterone concentrations in a juvenile male of a species may increase over time as they come into sexual maturity, a positive trend.

also in 7,469 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.