Circulating extracellular vesicles from early-stage lung cancer patients trigger endothelial activation to drive pre-metastatic niche formation through synergistic miR-29a and C4A signaling.

J Exp Clin Cancer Res · 2026 · PMC13340091 · PMID 42129855

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a clear trendno p-value reported

A clear trend was observed in the migration of neutrophils towards CM from ESD-treated endothelial cells compared to CM from controls’ cells, although the difference was not statistically significant (Fig. 2 H).

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