Barely Significant
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Endogenous neuroprotection in vascular cognitive impairment and dementia.

EBioMedicine · 2026 · PMC13342971 · PMID 42378963

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an important trendno p-value reported
7 , 8 Aggregation of these trials indicates that in direct comparison to standard pharmacologic treatment, nonpharmacologic interventions exhibit increased relative benefit alongside only a low-moderate risk of bias, largely from issues regarding blinding and sample size, 6 , 7 , 8 illustrating an important trend regarding the relative clinical promise of nonpharmacological interventions.

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