Barely Significant
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Temperature-related indicators and risk of incident cardiovascular-kidney-metabolic multimorbidity in middle-aged and older adults: a longitudinal cohort study from CHARLS.

Front Public Health · 2026 · PMC13346223 · PMID 42428937

Europe PMCDOI
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0.0900
closest p · 1.8× alpha
0.0900
boldest claim

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near-significantp = 0.09so close (0.05 < p ≤ 0.1)
tive quadratic term that did not reach statistical significance at the α = 0.05 level (OR = 0.00, 95% CI: 0.00–0.92, p = 0.06), and the core risk factors for CKM multimorbidity in this region included age, CESD-10 score, and baseline BMI; in cold regions, the linear term of the association showed a near-significant positive trend (OR = 1.56, p = 0.09), with no statistically significant effects observed in RCS interaction terms, and the core risk factors were age, CESD-10 score, and household registration type (OR = 1.87, p < 0.001); In temperate regions (central cities), RCS analyses showed no statistically s

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