Furagin Derivatives-Nitrofuran-Based Hydrazones as Potential Dual Inhibitors of Thioredoxin Reductase and Carbonic Anhydrases.

ChemMedChem · 2026 · PMC13346340 · PMID 42420762

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a clear trendno p-value reported

– For the disubstituted phenyl derivatives ( 7l – 7s ), a clear trend was observed in which the 2,5‐disubstituted analogs ( 7p–7r ) displayed moderate rTrxR1 inhibition, with IC 50 values ranging from 165 to 43 μM .

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