Hippocampal atrophy in untreated de novo Parkinson's disease with obstructive sleep apnea.

NPJ Parkinsons Dis · 2026 · PMC13346879 · PMID 42086584

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did not reach statistical significanceno p-value reported

Specifically, in the PD group, OSA+ subjects had significantly reduced both right ( p < 0.001) and left ( p < 0.001) hippocampal volumes compared to OSA− subjects, whereas in the CON group the difference between the hippocampal volumes of OSA+ and OSA− subjects did not reach statistical significance (Fig. 1 , Table 2 , Supplementary Data 1 ).

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