Sodium Bicarbonate versus N-Acetylcysteine plus hydration versus hydration alone for preventing contrast-associated acute kidney injury: A single-center retrospective analysis with propensity score matching.

PLoS One · 2026 · PMC13349148 · PMID 42424354

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0.1210

closest p · 2.4× alpha

0.1210

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did not reach statistical significanceP = 0.121not close (p > 0.1)

Sodium bicarbonate showed a numerically lower CA-AKI incidence than control, but the difference did not reach statistical significance after correction (RR = 0.50, 95% CI: 0.19–1.31, adjusted P = 0.121).

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