Efficacy and safety of rupatadine in allergic rhinitis: a systematic review and meta-analysis of randomized controlled trials.

Ann Med Surg (Lond) · 2026 · PMC13354435 · PMID 42433781

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failed to reach statistical significanceno p-value reported

Although symptom-based outcomes were significantly improved, QoL metrics failed to reach statistical significance in the pooled analysis.

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an increasing trendno p-value reported

Moreover, the prevalence shows an increasing trend every year [ 3 , 4 ] .

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