Risk factors for short-term survival in <i>EGFR</i>-mutated non-small cell lung cancer with brain metastasis and prognosis of the leptomeningeal metastasis subgroup: a retrospective cohort study.

Overall, the incidence of both BM and LM in EGFR -mutated patients continues to show an increasing trend ( 6 ).

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The results of the multivariate analysis were consistent with the survival curves mentioned above, as no independent risk factors significantly associated with short-term survival were identified; however, the use of third-generation EGFR-TKIs similarly showed a strong trend towards a protective effect (OR =0.29) ( Figures 3,4 ).

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