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Gut microbiota-dependent mechanisms and efficacy of natural polysaccharides in multitarget antidepressant therapy: a systematic review.

Front Psychiatry · 2026 · PMC13357710 · PMID 42445542

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a clear trendno p-value reported
The microbiota composition of the polysaccharide treatment group differed from that of the depression model group and exhibited a clear trend of aggregation or convergence compared with the healthy control group.

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