Barely Significant
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Genetic Risk for Depression Associates with Circulating Immunoregulatory Natural Killer Cells Independent of BMI: An Exploratory Immunophenotyping Study.

Cells · 2026 · PMC13359601 · PMID 42439656

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nominally significantno p-value reported
The most consistent signal involved the immunoregulatory CD56 bright CD16 − NK cell subset, which showed nominally significant positive correlations with the d-GRS across two independent parent gate representations, the percentage of viable DAPI − cells ( ρ = 0.444, 95%CI [0.158–0.661], p = 0.004, n = 41) and the percentage of CD45 + leukocytes ( ρ = 0.342, 95%CI [0.038–0.588], p = 0.029, n = 41; Figure 1 B; Table 3 ).

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